Nutrients |
Palmitoylethanolamide |
Inhibits BiP expression and the activation of PERK-eIF2α pathway |
Vitamin A |
Own anti-fibrillogenic effects |
β-Carotene |
Coenzyme Q10
|
Herbals and phytochemicals |
Crocin |
Decreases CHOP and BiP/Grp78 expressions, and inhibits the activation of pro-apoptotic factor caspase-12 |
Epigallocatechin-3-gallate (EGCG) |
Owns anti-fibrillogenic effects |
Baicalein |
Prevents α-Syn fibrillation, induces autophagy, inhibits apoptosis, and reduces inflammation |
Rosmarinic acid |
Owns anti-fibrillogenic effects |
Resveratrol |
Enhances α-Syn autophagic degradation |
Gallic acid |
Termed also as disaggregases, inhibit the aggregation of α-Syn fibrils |
Ginsenosides |
Salidroside |
Reduces α-Syn aggregation, enhancing the dephosphorylation of Ser129 |