Table 2.

Associations between [¹⁸F]-FEPPA binding and WTC exposures.

Region Name		PTSD severity			Total months on WTC site
	B ​± ​SE	d	P	B ​± ​SE	d	P
Frontal cortex	0.014 ​± ​0.004	0.71	0.001∗∗	0.030 ​± ​0.014	0.49	0.029∗
Parietal cortex	0.012 ​± ​0.005	0.60	0.007∗∗	0.032 ​± ​0.015	0.50	0.027∗
Temporal cortex	0.011 ​± ​0.007	0.53		0.140	0.035 ​± ​0.023	0.41 0.136
Occipital cortex	0.011 ​± ​0.005	0.33	0.018∗	0.027 ​± ​0.014	0.33	0.065#
Cingulate cortex	0.011 ​± ​0.005	0.51	0.025∗	0.025 ​± ​0.015	0.37	0.106
Hippocampus	0.014 ​± ​0.004	0.75	0.001∗∗	0.017 ​± ​0.013	0.28	0.208
Whole brain	0.012 ​± ​0.005	0.58	0.010∗	0.026 ​± ​0.015	0.39	0.080#

Note: Regression models showing the relationship between WTC exposures (i.e., PTSD symptom severity and total month working on the WTC sites) and [¹⁸F]-FEPPA V_T in the frontal cortex, temporal cortex, parietal cortex, occipital prefrontal cortex, hippocampus, and whole brain (not PVC) in WTC responders. GLM resulted beta coefficients (B), standard error for the beta coefficients (SE), Cohen's d (d) and nominal p-values (P) are reported. ^#0.1 ​> ​P ​> ​0.5, ∗P ​< ​0.05 and ∗∗P ​< ​0.01.

Abbreviations: V_T ​= ​total distribution volume.