Table 6.
Cognitive assessment.
CANTAB Test (unit of measurement) | Intervention | Study Period | Mean ± SEM | Baseline Comparison∗ | Exam Stress$ | Placebo v 1714% |
---|---|---|---|---|---|---|
PAL Total Errors adjusted | Placebo | Baseline | 3.80 ± 0.70 | NS | ||
(no. of errors) | Exam Stress | 2.42 ± 0.54 | NS | NS | ||
B. longum | Baseline | 2.26 ± 0.58 | ||||
Exam Stress | 2.30 ± 0.50 | NS | ||||
PAL total errors adjusted 8 | Placebo | Baseline | 2.00 ± 0.54 | NS | ||
(no. of errors) | Exam stress | 2.00 ± 0.46 | NS | NS | ||
B. longum | Baseline | 1.37 ± 0.39 | ||||
Exam stress | 1.75 ± 0.42 | NS | ||||
PAL Mean Trials to success | Placebo | Baseline | 1.32 ± 0.05 | NS | NS | |
(no. of trials) | Exam Stress | 1.26 ± 0.06 | NS | |||
B. longum | Baseline | 1.22 ± 0.05 | ||||
Exam Stress | 1.22 ± 0.05 | NS | ||||
RVP Total Hits | Placebo | Baseline | 21.40 ± 0.94 | NS | NS | |
(no. of hits) | Exam Stress | 23.30 ± 0.67 | ∗∗ | |||
B. longum | Baseline | 21.21 ± 0.79 | ||||
Exam Stress | 23.80 ± 0.68 | ∗∗∗ | ||||
RVP Total Misses | Placebo | Baseline | 5.60 ± 0.94 | NS | NS | |
(no. of misses) | Exam stress | 3.70 ± 0.67 | ∗∗ | |||
B. longum | Baseline | 5.79 ± 0.79 | ||||
Exam stress | 3.20 ± 0.68 | ∗∗∗ | ||||
RVP Mean Latency | Placebo | Baseline | 384.56 ± 15.63 | ∗ | NS | |
(milliseconds) | Exam stress | 356.81 ± 10.12 | NS | |||
B. longum | Baseline | 360.79 ± 11.20 | ||||
Exam stress | 355.26 ± 12.08 | NS | ||||
SSP Span Length | Placebo | Baseline | 7.65 ± 0.18 | NS | NS | |
(no. of stimuli recalled) | Exam stress | 8.30 ± 0.22 | ∗∗ | ∗ | ||
B. longum | Baseline | 7.60 ± 0.18 | ||||
Exam Stress | 8.50 ± 0.20 | ∗∗ | ||||
ERV Percent Correct | Placebo | Baseline | 75.97 ± 0.98 | NS | NS | |
(percentage) | Exam stress | 77.56 ± 1.02 | NS | |||
B. longum | Baseline | 76.03 ± 1.15 | ||||
Exam stress | 78.19 ± 1.03 | NS | ||||
Reading the Mind in the Eyes | Placebo | Baseline | 27.05 ± 0.70 | NS | ||
(score) | Exam stress | 28.05 ± 0.73 | NS | ∗ | ||
B. longum | Baseline | 27.55 ± 0.66 | ||||
Exam stress | 27.65 ± 0.73 | NS |
NS = not significant, ∗baseline comparison at visit 1 pre-treatment, $baseline versus exam stress, %placebo versus probiotic during exam period.