Table 6.
Cognitive assessment.
| CANTAB Test (unit of measurement) | Intervention | Study Period | Mean ± SEM | Baseline Comparison∗ | Exam Stress$ | Placebo v 1714% |
|---|---|---|---|---|---|---|
| PAL Total Errors adjusted | Placebo | Baseline | 3.80 ± 0.70 | NS | ||
| (no. of errors) | Exam Stress | 2.42 ± 0.54 | NS | NS | ||
| B. longum | Baseline | 2.26 ± 0.58 | ||||
| Exam Stress | 2.30 ± 0.50 | NS | ||||
| PAL total errors adjusted 8 | Placebo | Baseline | 2.00 ± 0.54 | NS | ||
| (no. of errors) | Exam stress | 2.00 ± 0.46 | NS | NS | ||
| B. longum | Baseline | 1.37 ± 0.39 | ||||
| Exam stress | 1.75 ± 0.42 | NS | ||||
| PAL Mean Trials to success | Placebo | Baseline | 1.32 ± 0.05 | NS | NS | |
| (no. of trials) | Exam Stress | 1.26 ± 0.06 | NS | |||
| B. longum | Baseline | 1.22 ± 0.05 | ||||
| Exam Stress | 1.22 ± 0.05 | NS | ||||
| RVP Total Hits | Placebo | Baseline | 21.40 ± 0.94 | NS | NS | |
| (no. of hits) | Exam Stress | 23.30 ± 0.67 | ∗∗ | |||
| B. longum | Baseline | 21.21 ± 0.79 | ||||
| Exam Stress | 23.80 ± 0.68 | ∗∗∗ | ||||
| RVP Total Misses | Placebo | Baseline | 5.60 ± 0.94 | NS | NS | |
| (no. of misses) | Exam stress | 3.70 ± 0.67 | ∗∗ | |||
| B. longum | Baseline | 5.79 ± 0.79 | ||||
| Exam stress | 3.20 ± 0.68 | ∗∗∗ | ||||
| RVP Mean Latency | Placebo | Baseline | 384.56 ± 15.63 | ∗ | NS | |
| (milliseconds) | Exam stress | 356.81 ± 10.12 | NS | |||
| B. longum | Baseline | 360.79 ± 11.20 | ||||
| Exam stress | 355.26 ± 12.08 | NS | ||||
| SSP Span Length | Placebo | Baseline | 7.65 ± 0.18 | NS | NS | |
| (no. of stimuli recalled) | Exam stress | 8.30 ± 0.22 | ∗∗ | ∗ | ||
| B. longum | Baseline | 7.60 ± 0.18 | ||||
| Exam Stress | 8.50 ± 0.20 | ∗∗ | ||||
| ERV Percent Correct | Placebo | Baseline | 75.97 ± 0.98 | NS | NS | |
| (percentage) | Exam stress | 77.56 ± 1.02 | NS | |||
| B. longum | Baseline | 76.03 ± 1.15 | ||||
| Exam stress | 78.19 ± 1.03 | NS | ||||
| Reading the Mind in the Eyes | Placebo | Baseline | 27.05 ± 0.70 | NS | ||
| (score) | Exam stress | 28.05 ± 0.73 | NS | ∗ | ||
| B. longum | Baseline | 27.55 ± 0.66 | ||||
| Exam stress | 27.65 ± 0.73 | NS |
NS = not significant, ∗baseline comparison at visit 1 pre-treatment, $baseline versus exam stress, %placebo versus probiotic during exam period.