Methodology |
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1.
Standardize inflammation data collection, storage, and processing procedures (e.g., time of blood draw, fasted samples, store all samples at the same temperature)
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2.
Increase investigation of measurement properties of immunological variables that are germane to immunopsychiatry designs (e.g., temporal stability, temporal specificity, dimensionality for aggregate measures)
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3.
Leverage knowledge of these measurement characteristics to plan data collection and analysis
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4.
Utilize statistical approaches that isolate theoretically-relevant variance to increase precision of inferences
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Phenotyping |
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1.
Diversify the level of psychopathological measurement (e.g., diagnostic cases, total scores, subscales, individual symptoms) to identify which level of measurement has the most robust associations with immunology
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2.
Similarly, explore the possibility for specific inflammatory proteins/processes to have differential relationships with psychopathology
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Theory Integration |
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1.
Increase conceptual and empirical work placing immunological processes in the context of established psychosocial risk frameworks for psychopathology (e.g., rumination, social stress)
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2.
Extend promising integrated etiological models to clinical research to establish maximally-comprehensive treatment plans
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