Table 3.
Multiple logistic regression model testing association of comorbidities with MDD-r or TRD adjusted to BMI and marital status.
| Association with MDD-r |
P | Association with TRD |
p | |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | |||
| Somatic comorbidities | ||||
| Arterial hypertension | 1.17 (1.03–1.33) | 0.013 | 1.34 (1.08–1.67) | 0.007 |
| Type 2 Diabetes | 1.07 (0.92–1.24) | 0.368 | 1.32 (0.97–1.85) | 0.058 |
| Ischemic heart disease | 1.44 (1.13–1.84) | 0.003 | 1.27 (0.83–1.94) | 0.256 |
| Chronic heart failure | 1.17 (0.83–1.65) | 0.346 | 1.49 (0.86–2.56) | 0.150 |
| COPD | 1.62 (1.29–2.05) | 0.001 | 1.70 (1.18–2.44) | 0.004 |
| Renal disease | 1.16 (0.80–1.69) | 0.406 | 0.96 (0.49–1.87) | 0.910 |
| Category (pooled) | ||||
| Allergic diseases | 1.24 (1.06–1.44) | 0.006 | 1.52 (1.19–1.94) | 0.001 |
| Systemic autoimmune diseases | 1.52 (1.04–2.24) | 0.030 | 2.22 (1.30–3.78) | 0.003 |
| Organ specific autoimmune diseases | 1.25 (1.04–1.49) | 0.013 | 1.49 (1.12–1.97) | 0.005 |