Table 2.

The change trend comparison of IVIM parameters between rat groups over time

		Time		Time*Group		Intersubjective
		F1	P1	F2	P2	F3	P3
CO	D	0.34	0.799	3.38	0.031	13.45	0.004
	D*	4.09	0.015	3.50	0.028	30.49	<0.001
	f	4.58	0.009	0.71	0.556	5.04	0.049
	ADC	54.37	<0.001	10.66	<0.001	0.00	0.974
OS	D	1.50	0.244	1.75	0.192	0.00	0.093
	D*	7.47	0.001	1.92	0.147	0.05	0.822
	f	12.19	<0.001	0.94	0.433	2.38	0.154
	ADC	52.86	<0.001	14.20	<0.001	0.29	0.604
IS	D	8.97	0.002	0.60	0.562	0.11	0.743
	D*	11.76	<0.001	5.07	1.006	1.20	0.300
	f	21.96	<0.001	1.17	0.337	0.08	0.782
	ADC	6.98	0.002	11.02	<0.001	34.49	<0.001
IM	D	1.37	0.280	0.26	0.738	4.81	0.053
	D*	0.76	0.530	1.98	0.139	35.37	<0.001
	f	5.22	0.005	0.67	0.580	5.94	0.035
	ADC	4.05	0.016	3.67	0.023	25.40	0.001

Note: D true diffusivity, D* pseudodiffusion coefficient, f perfusion fraction, ADC apparent diffusion coefficient. Data are presented as the mean ± standard deviation. The P values in bold type are of statistical significance. D, ADCs are presented in × 10⁻⁵ mm²/s, D* is presented in × 10⁻³ mm²/s, and f is presented as a percentage. CO, renal cortex, OS, outer stripe of the outer medulla, IS, inner stripe of the outer medulla, IM, internal medulla

P₁ indicates a difference in the changes in IVIM parameters over time between the two groups

P₂ indicates a difference in the difference of the IVIM parametric means between the two groups over time

P₃ indicates a difference in the IVIM parametric means between the two groups