Table 3.

IVIM parameters between rat groups at different time

			0 week	4 week	8 week	12 week
CO	D	Control	176.55±12.42	155.83±13.12	151.33±9.79	176.67±20.50
		DM	164.73±15.14	176.50±20.25	1778.67±18.15	173.33±17.70
		t/P	0.43/0.530	9.07/0.013	1.31/0.279	0.49/0.501
	D*	Control	11.01±2.66	11.70±1.49	10.37±1.06	12.40±1.24
		DM	10.48±1.99	17.81±2.23	15.40±5.46	14.07±2.31
		t/P	1.02/0.336	1.07/0.325	1.70/0.222	2.65/0.135
	f	Control	31.20±4.99	33.18±2.00	33.85±2.14	35.67±4.33
		DM	27.05±5.40	2.53±4.18	29.53±4.02	32.73±1.13
		t/P	0.67/0.434	0.06/0.817	0.04/0.850	0.10/0.762
	ADC	Control	178.79±4.48	216.17±9.07	199.50±5.96	230.83±9.52
		DM	176.00±8.32	210.17±11.43	224.33±5.47	214.50±13.40
		t/P	1.39/0.266	2.13/0.175	8.98/0.013	5.39/0.043
OS	D	Control	167.76±11.81	171.83±15.57	157.33±9.79	176.67±20.51
		DM	165.00±9.27	184.33±14.36	178.67±18.15	173.33±17.7
		t/P	0.27/0.613	3.34/0.098	2.55/0.142	0.13/0.730
	D*	Control	15.96±2.39	16.27±2.84	10.28±0.81	13.20±5.68
		DM	14.98±3.60	17.15±5.10	13.78±4.41	11.37±4.04
		t/P	0.02/0.896	1.49/0.251	0.82/0.388	1.54/0.243
	f	Control	24.85±3.00	32.43±5.17	28.20±3.22	34.35±3.46
		DM	23.15±2.83	30.35±4.16	29.53±3.17	30.65±3.84
		t/P	0.16/0.698	0.12/0.738	1.69/0.233	0.08/0.790
	ADC	Control	176.09±10.69	213.67±9.48	194.00±6.00	233.67±8.82
		DM	177.00±7.46	213.33±9.03	220.67±3.98	210.17±11.62
		t/P	0.02/0.899	3.33/0.098	1.62/0.231	23.02/0.001
IS	D	Control	209.11±15.09	187.67±14.46	175.33±11.55	194.00±21.43
		DM	210.0±15.58	187.33±13.52	180.50±15.50	183.00±9.96
		t/P	0.60/0.475	0.02/0.891	0.78/0.398	0.65/0.438
	D*	Control	16.57±1.27	16.60±1.19	10.12±1.61	10.86±1.16
		DM	14.44±3.07	15.78±3.62	11.30±3.61	16.13±3.14
		t/P	2.16/0.172	0.10/0.754	0.03/0.864	2.73/0.129
	f	Control	18.13±2.35	28.05±5.68	30.93±4.18	34.53±8.28
		DM	17.28±3.12	29.82±3.42	33.52±3.86	30.03±3.79
		t/P	0.71/0.419	0.03/0.858	1.19/0.301	0.03/0.869
	ADC	Control	211.13±5.06	228.50±18.09	196.17±21.87	260.50±17.90
		DM	210.00±4.15	214.17±10.21	219.50±16.81	209.50±9.85
		t/P	0.06/0.812	0.68/0.429	0.00/1.000	26.81/<0.001
IM	D	Control	202.50±10.86	200.67±8.73	203.83±9.09	220.83±49.14
		DM	207.83±4.54	224.50±9.33	223.17±41.97	233.83±33.23
		t/P	1.23/0.290	20.86/0.001	1.22/0.300	0.29/0.600
	D*	Control	15.02±1.68	13.60±2.84	13.84±2.44	12.20±1.44
		DM	15.73±2.67	14.68±2.90	17.50±3.37	17.48±1.96
		t/P	0.39/0.550	0.43/0.530	4.63/0.057	28.23/<0.001
	f	Control	12.80±1.20	18.15±3.54	19.13±2.03	17.26±4.02
		DM	13.60±2.65	25.50±1.58	25.51±15.02	20.53±7.26
		t/P	0.45/0.520	21.59/0.001	1.06/0.330	0.93/0.360
	ADC	Control	218.67±7.87	219.17±8.45	221.33±6.25	222.50±7.58
		DM	215.00±8.37	264.17±17.03	246.33±33.27	246.00±27.26
		t/P	0.61/0.450	33.61/<0.001	3.27/0.100	4.14/0.070

Note: D true diffusivity, D* pseudodiffusion coefficient, f perfusion fraction, ADC apparent diffusion coefficient. Data are presented as the mean ± standard deviation. The P values in bold type are of statistical significance. D, ADCs are presented in × 10⁻⁵ mm²/s, D* is presented in × 10⁻³ mm²/s, and f is presented as a percentage. CO renal cortex, OS outer stripe of the outer medulla, IS inner stripe of the outer medulla, IM internal medulla