Table 2.
Patient characteristics and basic treatment.
| n | Overall |
Mechanically ventilated |
||||
|---|---|---|---|---|---|---|
| non-COVID 627 | COVID 602 | p value | non-COVID 339 | COVID 458 | p value | |
| Age (years), n(%) | <0.0001∗ | <0.0001∗ | ||||
| x <20 | 54 (8.6) | 4 (0.7) | 30 (8.9) | 1 (0.2) | ||
| 20≤ x <30 | 28 (4.5) | 8 (1.3) | 13 (3.8) | 6 (1.3) | ||
| 30≤ x <40 | 51 (8.1) | 30 (5.0) | 26 (7.7) | 23 (5.0) | ||
| 40≤ x <50 | 57 (9.1) | 65 (10.8) | 28 (8.3) | 47 (10.3) | ||
| 50≤ x <60 | 90 (14.4) | 132 (21.9) | 50 (14.8) | 105 (22.9) | ||
| 60≤ x <70 | 120 (19.1) | 193 (32.1) | 77 (22.7) | 152 (33.2) | ||
| 70≤ x <80 | 136 (21.7) | 146 (24.3) | 64 (18.9) | 109 (23.8) | ||
| x ≥80 | 91 (14.5) | 24 (4.0) | 51 (15.0) | 15 (3.3) | ||
| Male, n (%) | 391 (62.4) | 425 (70.6) | 0.0022∗ | 209 (61.7) | 329 (71.8) | 0.0025∗ |
| BMI (kg/m2), n(%) | <0.0001∗ | <0.0001∗ | ||||
| x <18.5 | 84 (13.4) | 10 (1.7) | 49 (14.5) | 4 (0.9) | ||
| 18.5≤ x <25 | 310 (49.4) | 150 (24.9) | 147 (43.4) | 104 (22.7) | ||
| 25≤ x <30 | 155 (24.7) | 218 (36.2) | 99 (29.2) | 168 (36.7) | ||
| 30≤ x <35 | 54 (8.6) | 140 (23.3) | 27 (8.0) | 114 (24.9) | ||
| x ≥35 | 24 (3.8) | 84 (14.0) | 17 (5.0) | 68 (14.9) | ||
| ICU length of stay (days) | 5 (2, 10) | 9 (4.5, 16) | <0.0001∗ | 6 (2, 12) | 9 (5, 16) | <0.0001∗ |
| Use of support devices, n(%) | ||||||
| Extracorporeal membrane oxygenation | 18 (2.9) | 30 (5.0) | 0.055 | 12 (3.5) | 24 (5.2) | 0.25 |
| Renal replacement therapy | 66 (10.59) | 56 (9.3) | 0.47 | 41 (12.1) | 54 (11.8) | 0.90 |
| Left ventricular unloading device (ImpellaⓇ, IABP) | 10 (1.6) | 1 (0.2) | 0.0041∗ | 7 (2.1) | 1 (0.2) | 0.0076∗ |
| Continuous use of neuromuscular blockage, n(%) | 19 (3.0) | 159 (26.4) | <0.0001∗ | 15 (4.4) | 159 (34.7) | <0.0001∗ |
| Continuous use of vasoactive drugs, n(%) | 208 (33.2) | 186 (30.9) | 0.39 | 155 (45.7) | 180 (39.3) | 0.070 |
| Continuous use of analgesia and sedation agents, n(%) | 329 (52.5) | 394 (65.5) | <0.0001∗ | 242 (71.4) | 370 (80.8) | 0.0020 |
| Prone positioning (hours), n(%) | <0.0001∗ | <0.0001∗ | ||||
| 0 (not done) | 191 (30.5) | 333 (55.3) | 143 (42.2) | 266 (58.1) | ||
| 0≤ x <6 | 11 (1.8) | 58 (9.6) | 6 (1.8) | 42 (9.2) | ||
| 6≤ x <12 | 2 (0.3) | 38 (6.3) | 2 (0.6) | 25 (5.5) | ||
| 12≤ x <18 | 4 (0.6) | 57 (9.5) | 4 (1.2) | 51 (11.1) | ||
| 18≤ x ≤24 | 0 (0) | 56 (9.3) | 0 (0) | 53 (17.3) | ||
| Not a candidate (no respiratory failure) | 419 (66.8) | 60 (10.0) | 184 (54.3) | 21 (4.6) | ||
COVID, coronavirus disease; BMI, body mass index; IABP, intra-aortic balloon pump. ∗ infers a significant difference with p <0.05.