Table 4.
Association of perinatal data and severe functional disability at 24 month of corrected age.
| Univariate model | Multivariate model | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| Birth weight | 0.99 | 0.99–0.99 | <0.001 | |||
| Gestational age | 0.76 | 0.67–0.85 | <0.001 | 0.79 | 0.67–0.90 | 0.001 |
| Outborn | 2.66 | 0.84–8.36 | 0.094 | |||
| Maternal age | 0.95 | 0.90–0.99 | 0.035 | |||
| Ethnicity | 0.97 | 0.55–1.69 | 0.910 | |||
| Multiple gestation | 0.69 | 0.35–1.34 | 0.273 | |||
| APGAR 1st min | 0.83 | 0.72–0.94 | 0.006 | |||
| APGAR 5th min | 0.85 | 0.70–1.02 | 0.087 | |||
| Male gender | 1.94 | 1.04–3.60 | 0.036 | 1.94 | 0.99–3.77 | 0.052 |
| Mode of delivery | 1.71 | 0.86–3.37 | 0.122 | |||
| Prenatal steroids exposure | 0.96 | 0.32–2.81 | 0.936 | |||
| Chorioamnionitis | 2.23 | 1.16–4.25 | 0.015 | |||
| Sepsis | 4.26 | 2.11–8.59 | <0.001 | 2.23 | 0.99–4.98 | 0.050 |
| Mechanical ventilation | 4.16 | 2.19–7.89 | <0.001 | |||
| Periventricular-intraventricular hemorrhage | 4.66 | 2.42–8.98 | <0.001 | 2.51 | 1.19–5.26 | 0.015 |
| Periventricular leukomalacia | 16.12 | 4.88–53.15 | <0.001 | |||
| Pharmacological treatment for PDA | 2.23 | 1.21–4.12 | 0.010 | |||
| Surgical treatment for PDA | 2.37 | 1.30–4.32 | 0.005 | |||
| Necrotizing enterocolitis | 3.94 | 1.34–11.59 | 0.013 | |||
| ROP surgical treatment | 14.93 | 4.93–45.16 | <0.001 | |||
| Human milk feeding at discharge | 0.35 | 0.19–0.64 | 0.001 | |||
PDA, patent ductus arteriosus; ROP, retinopathy of the prematurity.
Missing cases were excluded from the statistical analyses.
The values in bold are statistically significant (p < 0.05).