Recommendation 8

Post-oophorectomy care should be administered in an individualized manner, ensuring optimal QoL, bone health, and cardiovascular risk amelioration. This is endorsed from Jacobson et al. 2018 [23].

Qualifying Statements for Recommendation 8

• Because of the increased risk of osteoporosis following pre-mature menopause, undergoing dual x-ray absorptiometry scan one year following RRSO is suggested, then determining the future frequency based on those results.

• Cardiovascular disease risk should be followed and ameliorated by the primary care practitioner or internist, while encouraging healthy lifestyle choices for these women.

Key Evidence for Recommendation 8

We endorse the recommendations from the clinical practice guideline conducted by Jacobson et al. [23] on behalf of the SOGC. This guideline scored well on the AGREE II scale. The scores are reported in Table 4–3 in Section 4 of this document. The evidence underpinning the recommendations is based on expert opinion.

Justification for Recommendation 8

The Working Group members are confident in their endorsement of the recommendation. The source had adequate quality ratings, there is an excellent alignment with research questions of interest to the Working Group, methods and evidence and synthesis are convincing, and the treatments and patients included in the evidence base are generalizable to the Ontario context.