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. 2021 Sep 26;10:137. doi: 10.1186/s13756-021-01008-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — a Maximum-likelihood tree depicting sequenced samples and amino-acid differences between reinfection sequences. Red indicates outbreak samples. Blue circles reflect sequences derived from reinfection case. Boxes indicate the amino-acid changes relative to the Wuhan-1 reference genome along the indicated branches. Contemporaneous background sequences were derived from GISAID and are depicted as grey branches. b B.1.1.7 clade of a with focus on outbreak sequences. Red indicates outbreak samples. Purple dots represents a collection of collapsed branches of background sequences. When samples were unavailable at day-of-detection, samples collected at day of return-to-work were used where available. Contemporaneous background sequences were derived from GISAID and are depicted as grey branches