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. 2021 Aug 7;10(16):e020893. doi: 10.1161/JAHA.120.020893

Table 3.

Physician Questionnaire (n=113)

Lipid Management Goals
LDL‐C goal to achieve with cholesterol‐lowering therapy
<50 mg/dL 4.5% (5/112)
<70 mg/dL 68.8% (77/112)
<100 mg/dL 10.7% (12/112)
<130 mg/dL 0.9% (1/112)
It depends on patient's other risk factors 8.9% (10/112)
Do not use LDL‐C goals 6.3% (7/112)
Choice for patients with very low LDL‐C
Make no change to lipid‐lowering therapy 49.1% (54/110)
Reduce, discontinue, or change the lipid‐lowering medication intensity 50.9% (56/110)
How strong is the scientific evidence supporting the use of high‐intensity statins vs low/moderate‐intensity statins among patients with ASCVD?
Very strong 43.6% (48/110)
Strong 34.5% (38/110)
Moderate 20.0% (22/110)
Weak/very weak 1.8% (2/110)
Barriers to Lipid Control
Frequently discuss adherence issues (most or always) 85.6% (95/111)
% of patients with statins experience side effects (mean±SD) 19.5%±13.2
Among patients who have muscle pain or aches while taking statins, what % do you think is due to statin? (mean±SD) 34.6%±23.9
Most common reason for nonadherence to statin
Patients don't believe the medication works 66.4% (75/113)
Patients can't afford the medication 8.8% (10/113)
Patients experienced side effects 0.9% (1/113)
Patients don't like taking medications 16.8% (19/113)
Other 7.1% (8/113)
Frequency of actions when a patient with ASCVD reports side effects while taking statins (most or all of the time)
Down‐titrate intensity 38.4% (43/112)
Give the patient 2 to 4 wk without statins and then re‐challenge them 37.5% (42/112)
Discontinue treatment 1.8% (2/112)
Educate patients on the importance of statins 86.6% (97/112)
Switch statin type 43.8% (49/112)
Advise patients to take the medication every other day 9.8% (11/112)
Add a supplement (eg, CO‐Q10 or vitamin D) 21.4% (24/112)
Frequency of prescribing nonstatin lipid‐lowering therapy for the following scenarios (most or always)
Patients cannot tolerate statins 59.8% (67/112)
LDL‐C remains high despite statin use 67.0% (75/112)
Further cardiovascular disease risk reduction above and beyond statin use 50.9% (57/112)

ASCVD indicates atherosclerotic cardiovascular disease; and LDL‐C, low‐density lipoprotein cholesterol.