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. 2021 Jun 12;106(10):2962–2978. doi: 10.1210/clinem/dgab424

Table 2.

Agents selected for retesting

Inhibition category Agents
Antifolates Pralatrexate
HDAC inhibitor JNJ-26481585, LBH-589, NVP LAQ824
HSP90 inhibitor NVP AUY922
Microtubule inhibitor Cabazitaxel, docetaxel, paclitaxel, vinblastine sulfate, vincristine sulfate
PLK1 inhibitor BI 2536
Proteasome inhibitor BORTEZOMIB, carfilzomib
Protein kinases inhibitor STAUROSPORINE
Pyrimidine analog Gemcitabine hydrochloride
ROS inducer ELESCLOMOL
Topoisomerase inhibitor Mitoxantrone

Agents were selected after stringent statistical analysis from 257 potential candidates. They were listed by their inhibitory mechanisms.

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