Table 2.
Agents selected for retesting
Inhibition category | Agents |
---|---|
Antifolates | Pralatrexate |
HDAC inhibitor | JNJ-26481585, LBH-589, NVP LAQ824 |
HSP90 inhibitor | NVP AUY922 |
Microtubule inhibitor | Cabazitaxel, docetaxel, paclitaxel, vinblastine sulfate, vincristine sulfate |
PLK1 inhibitor | BI 2536 |
Proteasome inhibitor | BORTEZOMIB, carfilzomib |
Protein kinases inhibitor | STAUROSPORINE |
Pyrimidine analog | Gemcitabine hydrochloride |
ROS inducer | ELESCLOMOL |
Topoisomerase inhibitor | Mitoxantrone |
Agents were selected after stringent statistical analysis from 257 potential candidates. They were listed by their inhibitory mechanisms.