Skip to main content
. 2021 Sep 27;28:67. doi: 10.1051/parasite/2021063

Table 4.

Multivariate analysis of risk factors associated with the occurrence of treatment failures.

Logistic model Failure (%) Odds ratio [CI 95%] p-value
Half-life (hours)
 < 5 h 40 (10.4) 1
 > 5 h 6 (21.4) 3.69 [1.18–10.3] 0.01
Hemoglobin type
 AA 40 (6.2) 1
 AC 4 (6.7) 1.5 [0.21–6.25] 0.62
 AS 1 (2.1) 0.54 [0.02–2.94] 0.56
 CC 1 (20.0) 11.74 [0.54–104] 0.04
 SC 0 (0.0) 0 0.99
 SS 0 (0.0) 0 0.99
Gender
 Female 18 (4.4) 1
 Male 28 (7.8) 1.57 [0.72–3.53] 0.25
Age group
 ≥ 5 years 16 (2.8) 1
 < 5 years 30 (14.6) 5.74 [2.6–13.1] 0.0001

Notes: Logistic regression stopped with Wald test 31.84 on 4 df (p = 2.066e−06). Only the variables age group (age < 5 years), parasite half-life, and HbCC were significantly linked with the risk of failure.