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Remdesivir inhibition of viral infection. (A) Titration of a single dose of remdesivir added at 1 h postinfection. Supernatant was collected 5 days postinfection. (B) Wells were treated every 24 h with the EC90 beginning at 24 hpi. EBOV EC90, 284.1 nM; BDBV EC90, 109.6 nM. (C and D) Wells were treated every 24 h with 12.5 μM remdesivir starting 24 hpi (C) or 48 hpi (D).
