Table 2.

Incidence rate of adverse events after each vaccination in Zagreb and Essen regimen

Observations (%)	Zagreb			Essen					P
	D0 N = 240	D7 N = 120	D21 N = 119	D0 N = 120	D3 N = 120	D7 N = 120	D14 N = 120	D28 N = 120
Local AEs	25 (5.22)			32 (5.33)
Total	18 (7.50)	6 (5.00)	1 (0.84)	14 (11.67)	7 (5.83)	7 (5.83)	3 (2.50)	1 (0.83)	0.934
Grade 1	17 (7.08)	6 (5.00)	1 (0.84)	14 (11.67)	7 (5.83)	7 (5.83)	3 (2.50)	1 (0.83)	0.812
Grade 2	1 (0.42)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0.444
Grade 3	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	–
Grade 4	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	–
Systemic AEs	10 (2.09)			8 (1.33)
Total	10 (4.17)	0 (0.00)	0 (0.00)	6 (5.00)	2 (1.67)	0 (0.00)	0 (0.00)	0 (0.00)	0.336
Grade 1	7 (2.92)	0 (0.00)	0 (0.00)	5 (4.17)	2 (1.67)	0 (0.00)	0 (0.00)	0 (0.00)	0.671
Grade 2	2 (0.83)	0 (0.00)	0 (0.00)	1 (0.83)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0.588
Grade 3	1 (0.42)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0.444
Grade 4	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	0 (0.00)	–