Table 2.
Characteristics of G+LVH‐ Patients Versus Controls
|
Category Mean (SD) |
G+LVH‐ (n=45) |
Control (n‐26) |
P Value |
|---|---|---|---|
| Age, y | 37.2 (12.3) | 38.9 (11.7) | 0.788 |
| No. of men, % | 13 (28.9) | 14 (50%) | 0.085 |
| BSA, m2 | 1.84 (0.23) | 1.93 (0.21) | 0.100 |
| LA area indexed, cm2/m2 | 13.07 (2.2) | 12.6 (1.8) | 0.354 |
| AMVLi, mm/m2 | 12.52 (2.1) | 11.55 (1.6) | 0.030* |
| ≥2 LV crypts n (%) | 13 (28.9) | 0 (0) | <0.005* |
| LVEDVi, mL/m2 | 73.7 (14.0) | 78.0 (14.8) | 0.222 |
| LVESVi, mL/m2 | 21.0 (6.9) | 26.7 (6.2) | <0.005* |
| Ejection fraction (%) | 71.9 (5.5) | 65.8 (4.4) | <0.005* |
| Massi, g/m2 | 45.4 (9.9) | 52.6 (9.3) | <0.005* |
| SV, mL | 97.2 (21.2) | 99.5 (25.5) | 0.701 |
| Visual perfusion defects n (%) | 9 (20.0) | 0 (0) | 0.011* |
| Mean global stress MBF, mL/g per min | 2.75 (0.71) | 2.78 (0.9) | 0.826 |
| Mean MPR | 2.77 (0.83) | 3.24 (0.63) | 0.009* |
| Mean rest MBF, mL/g per min | 1.08 (0.37) | 0.9 (0.23) | 0.011* |
| Mean subendocardial MBF, mL/g per min | 2.52 (0.82) | 2.65 (0.69) | 0.457 |
| Mean subendocardial MPR | 2.55 (0.75) | 3.2 (0.65) | <0.005* |
| Mean subepicardial MBF, mL/g per min | 2.8 (0.73) | 2.84 (0.59) | 0.800 |
| Mean subepicardial MPR | 3.01 (0.96) | 3.47 (0.75) | 0.026* |
| Subendo:subepicardial MBF ratio | 0.898 (0.17) | 0.934 (0.14) | 0.329 |
| Subendo:subepicardial MPR ratio | 0.87 (1.84) | 0.93 (0.13) | 0.092 |
| Septal T1, ms | 1025.6 (34.6) | 1016.0 (31.7) | 0.231 |
| Septal T2, ms | 49.2 (3.8) | 47.7 (2.43) | 0.041* |
| Septal ECV (%) | 25.8 (2.4) | 24.3 (2.6) | 0.023* |
| MWT, mm | 9.03 (1.95) | 8.37 (1.2) | 0.075 |
| LGE present n (%) | 8 (17.8) | 0 (0%) | 0.020* |
AMVLi indicates indexed anterior mitral valve leaflet (length); BSA, body surface area; ECV, extracellular volume; G+LVH‐, genotype‐positive, left ventricular hypertrophy‐negative; LA, left atrium; LGE, late gadolinium enhancement; LV, left ventricle/ventricular; LVEDVi, indexed left ventricular end‐diastolic volume; LVESVi, indexed left ventricular end‐systolic volume; Massi, indexed mass; MBF, myocardial blood flow; MPR, myocardial perfusion reserve; MWT, maximum wall thickness; and SV, stroke volume.
*
indicates significant P value <0.05.