Dio2+ fibrocytes in proximity to medial vascular networks in Dio2CreERt2;Ai6 mice. A, Wholemount surface view showing Dio2+ fibrocytes (pale blue) clustered around vessels (CD31, magenta) in the spiral limbus. DAPI, general nuclear stain (dark blue). B, Simplified diagram (surface view) of vasculature in spiral limbus region. RAL, radiating arterioles extend into capillary networks in the spiral limbus and spiral lamina (below, not seen in this view); CV, collecting venules. C, Magnified surface view of Dio2+ fibrocytes with projections around limbus vessels. D, Section showing Dio2+ fibrocytes around limbus and lamina vessels. Abbreviations: CV, collecting venule; HC, hair cells; ise, inner sulcus epithelium; RAL, radiating arteriole; SMA, spiral modiolar artery; SMV, spiral modiolar vein.