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. 2021 Sep 4;162(12):bqab193. doi: 10.1210/endocr/bqab193

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© The Author(s) 2021. Published by Oxford University Press on behalf of the Endocrine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Increased expression of Dpp-4 gene after dexamethasone loading in mice is associated with histone hyperacetylation. (A) Expression of Proglucagon, PC1/3, and Dpp-4 in the small intestine. (B) Expression of Dpp-4 in the mononuclear cells collected from the serum. (C) Time course of histone acetylation in the promoter region of Dpp-4 gene in the mononuclear cells. H3Ac, histone H3 acetylation; H3K9Ac, histone H3 lysine-9 acetylation; H4Ac, histone H4 acetylation; H4K16Ac, histone H4 lysine-16 acetylation. *P < 0.05, **P < 0.01 vs control. N = 8 per group.