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. 2021 Sep 13;12:709804. doi: 10.3389/fphys.2021.709804

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Copyright © 2021 Sibomana, Foose, Raymer, Reo, Karl, Berryman, Young, Pasiakos and Mauzy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Urinary creatine levels for AMS susceptible (blue symbol) and NoAMS resistant subjects (black symbol) at SL, and 4,300m on day 1 (HA1) and day 18 (HA2) determined using the (A) ¹H NMR technique and (B) creatine assay. Asterisk denotes significant difference between groups (p≤0.05).