Table 1.

X-Ray Diffraction and Refinement Statistics

Data Collection	G12C-1
Space group	P3
Cell dimensions
a, b, c (Å)	84.93, 84.93, 130.79
α, β, γ (°)	90.00, 90.00, 120.00
Resolution (Å)	50.00–2.23 (2.27–2.23)
Rsym or Rmerge	0.183 (1.536)
I/sI	17.00 (1.33)
Completeness (%)	87.7 (48.0)
Redundancy	7.8 (5.0)
Refinement
Resolution (Å)	40.39–2.23
No. of reflections	45,197
Rwork/Rfree	0.189/0.230
No. of atoms
Protein	8,082
Ligand/ion	342
Water	375
B factors
Protein	42.10
Ligand/ion	32.09
Water	37.19
RMSD
Bond lengths (Å)	0.002
Bond angles (°)	0.596

RMSD, root-mean-square deviation.