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. 2021 Sep 27;16(9):e0253545. doi: 10.1371/journal.pone.0253545

Table 3. Gene set enrichment analysis.

Gene set name NES NOM p-val FDR q-val
HALLMARK_TNFA_SIGNALING_VIA_NFKB 1.74 0.024 0.046
HALLMARK_P53_PATHWAY 1.437 0.017 0.201
KEGG_GLUTATHIONE_METABOLISM -1.545 0.039 0.192
KEGG_CALCIUM_SIGNALING_PATHWAY -1.575 0.006 0.186
KEGG_WNT_SIGNALING_PATHWAY -1.596 0.010 0.173
KEGG_TGF_BETA_SIGNALING_PATHWAY -1.651 0.020 0.150
KEGG_MELANOGENESIS -1.698 0.010 0.141
KEGG_LYSOSOME -1.88 0.004 0.129

NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate. Gene sets with NOM p-val <0.05 and FDR q-val <0.25 are considered as significant.