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. 2021 Aug 7;80(9):835–843. doi: 10.1093/jnen/nlab073

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© 2021 American Association of Neuropathologists, Inc. All rights reserved.

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FIGURE 2. — Biochemical assessment of 3 and 4 repeat tau isoforms in essential tremor compared to AD and sporadic tauopathies. Representative immunoblots using isoform specific antisera targeting 3R (A) or 4R (B) on total protein lysates. The relative levels of 3R (C–E) and 4R (F–H) as well as the ratios of 4R : 3R (I–K) normalized to GAPDH are shown. Three data points of PSP cases in (F), 2 in (G), 2 in (I), and 1 in (J) are outside the axis limits (the values are 20.6, 34.6, 148.9 in [F]; 26.7, 107.1 in [G]; 5.0, 21.6 in [I]; 21.5 in [J]). PSP in (F), 26.7 ± 14.6 (SEM); PSP in (I), 3.8 ± 2.1 (SEM).