Table 3.
Chemopreventive Effect of Combined Drug Sample Against Skin Carcinogenesis Induced by DMBA and Croton Oil in Mice
| Treatment | Body Weight (gm) | Papillomas (n) | Tumor Size (mm) | Average Latency Period* | |
|---|---|---|---|---|---|
| Initial | Final | ||||
| Group I (normal control) | 38.12±4.23 | 37.56±5.43 | |||
| Group II (carcinogen control) | 26.26±2.16 | 22.75±11.24 | 10.16±5.03 | 2.06±0.37 | 10.10±5.17 |
| Group III (treated 100 mg/kg) | 28.23±2.34 | 23.80±13.23 | 1.09±0.77 | 0.58±0.20 | 18.59±0.72 |
| Group IV (treated 200kg/kg) | 27.56±2.12 | 22.87±11.65 | 0.65±0.28 | 0.24±0.05 | 19.96±0.89 |
Notes: *Average latency period: is Σ fx/n; f is the number of papillomas appearing every week; x is the number of weeks; n is the total number of papillomas.