Table 1.
Property profile of selected peptides against five selected receptor proteins.
| Sr. No. | Peptide | Receptor | S-score | RMSD | Interacting amino acids |
|---|---|---|---|---|---|
| 1 | KDDGHL | IR | -18.56 | 2.75 | Ser1270, Asp1143, Glu1108, Glu1115, His1057 |
| 2 | EPGGGG | IR | -16.71 | 1.85 | Arg B1026. Glu A186, Asp B1343, His B1057, Lys B1147, Ala B1050, Ser A187 |
| 3 | TSEP | IR | -15.66 | 1.21 | Asp1143, Thr1145, Glu1115, Arg1101, Glu1108 |
| 4 | VAEK | IR | -15.53 | 2.29 | Glu1115, His1058, Ser1270, Asp1143, Phe1144, Glu1108 |
| 5 | LIVA | IR | -14.00 | 1.73 | Thr A178, His B1057, Cys B1056, Val B1059, Glu B1077, Lys B1147 |
| 6 | ESIRD | SGLT1 | -23.81 | 2.86 | Thr431, ser368, Gln428, Asn142, Ser364, Ser66, Lys294, Gln69, Glu88 |
| 7 | DSRHR | SGLT1 | -23.64 | 2.46 | Thr431, Ser368. Gln428. Ser91, Lys294, Ser365, Gln268, Asn267, Asn64, Ser66 |
| 8 | RRKKV | SGLT1 | -20.64 | 2.92 | Thr431, Asn260, Asn267, Tyr263, Asn64, Ser435 |
| 9 | PTRHM | SGLT1 | -19.60 | 1.83 | Tyr263, Gln68, Ala63, Ser365 |
| 10 | DFGAS | SGLT1 | -9.3259 | 1.5980 | Asp189, Tyr176 |
| 11 | PTRHM | DPP-IV | -10.1067 | 2.5395 | Gln268, Thr375, Asn371 |
| 12 | RRKKV | DPP-IV | -9.9189 | 1.7598 | Val185, Asn267, Tyr269 |
| 13 | KDDGHL | DPP-IV | -9.4991 | 1.4528 | Ser368, Asn267, Val185 |
| 14 | RSIHEP | DPP-IV | -9.0877 | 1.7136 | Asn371, Val185 |
| 15 | VAEK | DPP-IV | -8.1677 | 2.3228 | Ser59, Ala63, Ser368 |
| 16 | RRKKV | GLUT2 | -10.5970 | 1.3552 | Met174, Glu361, Arg432 |
| 17 | RSIHEP | GLUT2 | -10.5171 | 2.4307 | Met174, Glu361 |
| 18 | ERFDSG | GLUT2 | -9.6986 | 1.7398 | Gln429, Phe421 |
| 19 | KDDGHL | GLUT2 | -9.5645 | 1.5598 | Glu282 |
| 20 | PTRHM | GLUT2 | -9.2187 | 1.4949 | Arg432 |