Table 2.
Distribution of first-line drug-resistance with Mycobacterium tuberculosis complex lineages and families among extrapulmonary TB (N = 151).
| Lineages (Ls) (n) | Sublineages | Resistance N (%) | |||||
|---|---|---|---|---|---|---|---|
| STR | INH | RIF | EMB | PZA | MDR-TB | ||
| Euro-American (L4) (111) | 5 (4.5) | 14 (12.6) | 8 (7.2) | 2 (1.8) | 14 (12.6) | 8 (7.2) | |
| T | 1 (0.9) | 2 (1.8) | 0 | 1 (0.9) | 2 (1.8) | 0 | |
| T3-ETH | 3 (2.7) | 10 (9.0) | 7 (6.3) | 1 (0.9) | 0 | 7 (6.3) | |
| Haarlem | 1 (0.9) | 1 (0.9) | 1 (0.9) | 0 | 3 (2.7) | 1 (0.9) | |
| X1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| LAM | 0 | 1 (0.9) | 0 | 0 | 2 (1.8) | 0 | |
| Ural | 0 | 0 | 0 | 0 | 1 (0.9) | 0 | |
| East-African-Indian (L3) [26] | CAS | 3 (11.5) | 5 (19.2) | 4 (15.4) | 0 | 6 (23.1) | 4 (15.4) |
| Indo-Oceanic (L1) [1] | EAI5 | 1 (100) | 1 (100) | 1 (100) | 0 | 0 | 1 (100) |
| East-Asian (L2) [1] | Beijing | 0 | 0 | 0 | 0 | 0 | 0 |
| Bovis [3] | BOV | 0 | 1 (33.3) | 0 | 0 | 1 (33.3) | 0 |
| Unknown strain [9] | Not defined | 0 | 1 (11.1) | 1 (11.1) | 1 (11.0) | 1 (11.1) | 1 (11.1) |
EA: Euro-American; EAI: East-African-Indian; IO: Indo-Oceanic; EAI: East-African-Indian; CAS: Central Asian Strain; H: Harlem; BOV: Bovis; LAM: Latin American Mediterranean; ETH: Ethiopia; L: lineages; STM: streptomycin; INH: isoniazid; RIF: rifampicin; EMB: ethambutol; PZA: pyrazinamide; MDR: multidrug resistance.