Table 2.
Characteristics of subjects at first and at last visit according to the number of altered components of SHATS (SHATS score) assessed at last visit
| First visit | Last visit | Visit | SHATS score | Visit* SHATS score | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||||
| Age (years) | 34.8 ± 11.9 | 43.5 ± 13.0 | 54.3 ± 11.2 | 65.3 ± 7.1 | 42.8 ± 12.6 | 53.2 ± 12.9 | 63.9 ± 11.3 | 75.4 ± 8.1 | |||
| BMI (Kg/m2) | 23.3 ± 3.5 | 26.0 ± 4.0 | 27.4 ± 3.2 | 28.1 ± 4.1 | 24.1 ± 3.8 | 26.8 ± 4.3 | 28.1 ± 3.5 | 27.7 ± 4.1 | 0.49 | 0.0001 | 0.54 |
| Waist circumference (cm) | 78.1 ± 10.4 | 85.3 ± 11.0 | 92.3 ± 9.1 | 94.7 ± 8.9 | 84.3 ± 10.1 | 90.5 ± 10.4 | 96.3 ± 8.8 | 97.6 ± 8.1 | 0.001 | 0.0001 | 0.13 |
| SBP (mmHg) | 118.1 ± 13.8 | 125.4 ± 16.4 | 132.8 ± 14.5 | 148.1 ± 18.3 | 114.8 ± 14.9 | 122.7 ± 16.5 | 133.1 ± 14.8 | 128.3 ± 13.1 | 0.01 | ||
| DBP (mmHg) | 73.2 ± 9.4 | 77.7 ± 10.4 | 82.5 ± 9.9 | 84.8 ± 9.9 | 71.3 ± 9.4 | 76.0 ± 10.1 | 78.3 ± 10.3 | 74.1 ± 9.3 | 0.05 | ||
| MBP (mmHg) | 88.0 ± 10.0 | 93.4 ± 11.5 | 99.1 ± 10.5 | 105.7 ± 11.8 | 85.7 ± 10.6 | 91.4 ± 11.5 | 96.4 ± 10.8 | 92.0 ± 9.9 | 0.05 | ||
| PP (mmHg) | 44.9 ± 9.9 | 47.7 ± 11.3 | 50.3 ± 10.9 | 63.3 ± 13.2 | 43.5 ± 9.8 | 46.7 ± 10.8 | 54.8 ± 10.9 | 54.2 ± 8.7 | 0.001 | ||
| Fasting glucose (mg/dl) | 84.4 ± 16.6 | 87.7 ± 15.5 | 95.1 ± 16.6 | 85.8 ± 10.6 | 91.8 ± 18.6 | 98.1 ± 24.5 | 107.1 ± 23.6 | 105.7 ± 18.9 | 0.05 | ||
| Total cholesterol (mg/dl) | 200.7 ± 39.7 | 213.9 ± 38.2 | 226.2 ± 37.2 | 229.6 ± 17.0 | 209.1 ± 41.5 | 217.4 ± 40.8 | 211.0 ± 44.2 | 222.5 ± 41.4 | 0.001 | ||
| LDL cholesterol (mg/dl) | 120.2 ± 32.0 | 131.7 ± 33.2 | 142.7 ± 30.8 | 141.1 ± 12.9 | 125.7 ± 35.6 | 133.3 ± 34.7 | 128.9 ± 37.9 | 141.5 ± 36.4 | 0.01 | ||
| HDL cholesterol (mg/dl) | 65.4 ± 14.5 | 64.6 ± 14.9 | 61.9 ± 13.7 | 67.5 ± 7.8 | 65.3 ± 14.7 | 63.5 ± 14.0 | 58.3 ± 12.6 | 61.1 ± 21.9 | 0.08 | 0.0001 | 0.28 |
| Triglycerides (mg/dl) | 73.8 ± 43.5 | 86.8 ± 50.2 | 108.0 ± 57.4 | 104.8 ± 56.4 | 88.6 ± 49.6 | 98.6 ± 52.9 | 113.7 ± 64.5 | 98.9 ± 40.9 | 0.06 | 0.0001 | 0.38 |
| Serum creatinine (mg/dl) | 0.78 ± 0.15 | 0.80 ± 0.20 | 0.93 ± 0.17 | 1.2 ± 0.9 | 0.83 ± 0.13 | 0.85 ± 0.18 | 1.05 ± 0.23 | 1.14 ± 0.18 | 0.01 | 0.0001 | 0.20 |
| Uric acid (mg/dl) | 3.8 ± 1.2 | 4.2 ± 1.4 | 5.2 ± 1.5 | 6.1 ± 1.4 | 4.3 ± 1.3 | 4.7 ± 1.3 | 5.6 ± 1.6 | 5.7 ± 1.2 | 0.18 | 0.0001 | 0.12 |
| Diabetes mellitus (%) | 1.1 | 1.9 | 6.7 | 0 | 3.3 | 6.7 | 13.1 | 28.5 | 0.001 | ||
| Obesity (%) | 4.9 | 15.1 | 18.1 | 30.0 | 8.2 | 20.8 | 26.2 | 28.5 | 0.43 | 0.0001 | 0.30 |
| Overweight (%) | 21.6 | 41.3 | 63.8 | 50.0 | 26.9 | 43.3 | 54.6 | 57.1 | 0.73 | 0.0001 | 0.14 |
| PWV (m/s) | 5.8± 1.4 | 6.7 ± 2.2 | 7.7 ± 2.0 | 9.2 ± 2.5 | 6.7 ± 1.8 | 7.7 ± 2.2 | 8.6 ± 2.5 | 9.9 ± 1.9 | 0.001 | 0.0001 | 0.81 |
| PWV > 10 m/s (%) | 1.6 | 6.5 | 10.3 | 30.0 | 2.5 | 7.4 | 11.5 | 35.7 | 0.81 | 0.0001 | 0.78 |
The column “Visit” indicates significance of differences in the variable between visits. The column “SHATS score” indicates significance of differences in the variable across SHATS score. The column with the interaction term “Visit*SHATS score” indicates that variable levels differ between visits according to the SHATS score