Table 2. Diagnostic criteria for definite autoimmune encephalitis.
(Table adapted from Graus et al., 2016 [8])
CSF = cerebrospinal fluid, MRI = magnetic resonance imaging, EEG = electroencephalogram
| All of the following | At least one of the following |
| Subacute onset (rapid progression of less than three months) of working memory deficits, seizures, or psychiatric symptoms suggesting the involvement of the limbic system | CSF pleocytosis (white blood cell count of more than five cells per mm3) |
| Bilateral brain abnormalities on T2-weighted fluid-attenuated inversion recovery MRI highly restricted to the medial temporal lobes | EEG with epileptic or slow-wave activity involving the temporal lobes |
| Reasonable exclusion of alternative causes |