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. 2021 Sep 28;27(36):6064–6078. doi: 10.3748/wjg.v27.i36.6064

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Knockdown of circRNA_0084927 inhibits the migration and invasion of HCT116 cells. A: Knockdown of circRNA_0084927 (circ_0084927); B: Vability of HCT116 cells after circ_0084927 knockdown; C-G: Migration and invasion of HCT116 cells tested by wound healing assay (C and D) and transwell assay (E-G). Data are presented as the mean ± SEM. ^bP < 0.01; ^cP < 0.001. Circ_0084927: CircRNA_0084927; Sh-circ_0084927: Short hairpin circ_0084927 plasmid; Sh-NC: Short hairpin negative control plasmid.