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. 2021 Sep 28;27(36):6064–6078. doi: 10.3748/wjg.v27.i36.6064

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Glutathione S-transferase mu 5 is a target of miRNA-20b-3p. A and B: Expression of glutathione S-transferase mu 5 (GSTM5) after transfecting miRNA-20b-3p (miR-20b-3p) mimic; C and D: Expression of GSTM5 after transfecting circRNA_0084927 (circ_0084927); E and F: Expression of GSTM5 after transfecting sh-circ_0084927 plasmid and miR-20b-3p inhibitor; G: Overall survival by GSTM5 expression. Data are presented as the mean ± SEM. ^aP < 0.05, ^bP < 0.01. NC mimic: Negative control mimic; GSTM5: Glutathione S-transferase mu 5; miR-20b-3p: miRNA-20b-3p; Sh-circ_0084927: Short hairpin circ_0084927 plasmid; Sh-NC: Short hairpin negative control plasmid.