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. 2021 Sep 28;27(36):6064–6078. doi: 10.3748/wjg.v27.i36.6064

Figure 6.

Figure 6

AKT-mTOR pathway is inactivated by circRNA_0084927 knockdown and rescued by miRNA-20b-3p. A: Expression of AKT-mTOR pathway molecules after transfecting miRNA-20b-3p (miR-20b-3p) mimic; B: Expression of AKT-mTOR pathway molecules after transfecting circRNA_0084927 (circ_0084927); C: Expression of AKT-mTOR pathway molecules after transfecting sh-circ_0084927 plasmid and miR-20b-3p inhibitor. Data are presented as the mean ± SEM. aP < 0.05; bP < 0.01. Sh-circ_0084927: Short hairpin circ_0084927 plasmid; Sh-NC: Short hairpin negative control plasmid; NC mimic: Negative control mimic.