Table 3.
Key genes in PC patients evaluated for mutational analysis
|
Mutation’s present
|
Mutation’s absent
|
P
value for mutations present vs absent
|
KRAS mutation (codon 12) | 16 | 34 | 0.05 |
KRAS mutation (codon 13) | 12 | 38 | 0.05 |
DPC-4 mutation (1203G>T) | 0 | 50 | 0.001 |
BRCA-2 mutation (6174delT) | 0 | 50 | 0.001 |
KRAS: Kirsten rat sarcoma; DPC-4: Deleted in pancreatic cancer-4; BRCA-2: Breast cancer type 2.