Table 2.
Comparison of the oldest (≥ 80 years) and younger aSDH patients
| All (no.[%]) | Oldest patients (no.[%]) | Younger patients (no.[%]) | OR (95% CI) | p value | |
|---|---|---|---|---|---|
| No. of patients | 54 | 27 (50) | 27 (50) | ||
| Demographic factors | |||||
| Median age in years (range) | 78 (19–93) | 84 (81–87) | 65 (19–75) | > 0.0001b | |
| Male sex | 32 (59) | 16 (59) | 16 (59) | NS | |
| Comorbidities | |||||
| Arterial hypertension | 34 (63) | 22 (81.5) | 12 (44) | 0.2 (0.1–0.6) | 0.01a |
| Atrial fibrillation | 20 (37) | 15 (55.5) | 5 (18.5) | 0.2 (0.1–0.6) | 0.01a |
| Comorbidities ≥ 5 | 12 (22) | 7 (26) | 5 (18.5) | NS | |
| Comorbidities ≤ 1 | 19 (35) | 5 (18.5) | 14 (52) | 4.7 (1.4–14.8) | 0.02a |
| Anticoagulation | 33 (61) | 23 (85) | 10 (37) | 0.1 (0.03–0.4) | 0.0006a |
| Clinical presentation and imaging | |||||
| Comatose on admission (GCS < 8) | 23 (43) | 11 (41) | 12 (44) | NS | |
| Anisocoria | 18 (33) | 11 (41) | 7 (26) | NS | |
| Midlineshift > 1 cm | 24 (44) | 12 (44) | 12 (44) | NS | |
| Median volume of SDH in ml (IQR) | 71 (52–105) | 92 (63–141) | 71 (52–105) | NS | |
| Rad. Sign of herniation | 20 (37) | 11 (41) | 9 (33) | NS | |
| Reversal of anticoagulation | 22 (41) | 14 (52) | 8 (30) | NS | |
| Details on surgery | |||||
| Median time to surgery in min (IQR) | 245 (111–628) | 245(105–1138) | 237 (118–571) | 0.0336b | |
| Median craniotomy diameter in cm (IQR) | 7 (5–8) | 7 (5–8) | 7 (5–8) | NS | |
| Subdural drains used | 25 (46) | 15 (55.5) | 10 (37) | NS | |
| ICP probe implanted | 14 (26) | 7 (26) | 7 (26) | NS | |
| Median duration of surgery in min (IQR) | 118 (90–141) | 125 (101–145) | 115 (83–133) | NS | |
| Postoperative course | |||||
| ICU treatment | 41 (76) | 22 (81.5) | 19 (70) | NS | |
| ICP therapy | 11 (20) | 4 (15) | 7 (26) | NS | |
| Surgical complications | 13 (24) | 7 (26) | 6 (22) | NS | |
| Rebleeding | 10 (18.5) | 6 (22) | 4 (15) | NS | |
| Wound infection | 2 (4) | 0 (0) | 2 (7) | NS | |
| Others | 1 (2) | 1 (4) | 0 (0) | NS | |
| Revision surgery | 11 (20) | 6 (22) | 5 (18.5) | NS | |
| Non-surgical complications | 26 (48) | 13 (48) | 13 (48) | NS | |
| Remote cerebellar hemorrhage | 1 (2) | 1 (4) | 0 (0) | NS | |
| Cardiovascular | 4 (7) | 3 (11) | 1 (4) | NS | |
| Pneumonia | 17 (31.5) | 7 (26) | 10 (37) | NS | |
| Respiratory insufficiency | 4 (7) | 2 (7) | 2 (7) | NS | |
| Postoperative seizures | 9 (17) | 6 (22) | 3 (11) | NS | |
| Median hospital stay in days (IQR) | 6 (4–10) | 6 (4–10) | 6 (4–11) | NS | |
| Outcome at discharge | |||||
| GOS of 4–5 at discharge | 18 (33) | 6 (22) | 12 (44) | NS | |
| In-hospital mortality | 12 (22) | 9 (33) | 3 (11) | NS | |
| Discharged home | 7 (13) | 1 (4) | 6 (22) | NS | |
| Transferred to other hospital | 35 (65) | 17 (63) | 18 (67) | NS | |
GCS Glasgow coma scale, GOS Glasgow outcome scale, SDH Subdural hematoma, ICP Intracranial pressure, ICU Intensive care unit, IQR Interquartile range, OR Odds ratio; CI Confidence interval, NS not significant
p > 0.05
aFisher exact test
bUnpaired t test