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GI50 values of CCT245718 in cancer cell lines of different origins in 3-day proliferation assays.
| Cell line | CCT245718 GI50 µM |
|---|---|
| MOLM-13 | 0.195 ± 0.048 (n = 4) |
| MV-4-11 | 0.191 ± 0.053 (n = 4) |
| THP1 | 6.11 ± 3.58 (n = 2) |
| HCT116 | 2.99 ± 1.33 (n = 3) |
| Kelly | 4.32 ± 0.96 (n = 3) |
| IMR-32 | 2.16 ± 0.59 (n = 3) |
| SHEP WT | 3.5 ± 1.09 (n = 3) |
