Table 5.
The interaction of BDNF Val/Met polymorphism and ORAC on anthropometric indices, lipid profile and atherogenic indices.
| Variable | Allele | High adherence of ORAC | |||
|---|---|---|---|---|---|
| β | 95% CI | P | |||
| BMI | Crud | Met/Met | 1.57 | − 0.88 to − 4.02 | 0.20 |
| Val/Met | 1.69 | 0.16 to 3.23 | 0.03 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | 1.62 | − 0.82 to 4.06 | 0.19 | |
| Val/Met | 1.84 | 0.31 to 3.37 | 0.01 | ||
| Val/Val | Reference | ||||
| WC | Crud | Met/Met | 1.75 | − 3.91 to 7.43 | 0.54 |
| Val/Met | 3.60 | 0.04 to 7.16 | 0.04 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | 1.50 | − 4.17 to 7.19 | 0.60 | |
| Val/Met | 3.75 | 0.19 to 7.31 | 0.03 | ||
| Val/Val | Reference | ||||
| HDL | Crud | Met/Met | − 5.50 | − 12.20 to 1.19 | 0.10 |
| Val/Met | − 4.71 | − 8.92 to − 0.51 | 0.02 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | − 5.09 | − 11.82 to 1.62 | 0.13 | |
| Val/Met | − 4.62 | − 8.83 to − 0.41 | 0.03 | ||
| Val/Val | Reference | ||||
| TG | Crud | Met/Met | − 0.23 | − 57.60 to 57.13 | 0.99 |
| Val/Met | 44.95 | 9.09 to 80.82 | 0.01 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | − 1.18 | − 59.34 to 56.98 | 0.96 | |
| Val/Met | 45.52 | 9.30 to 81.73 | 0.01 | ||
| Val/Val | Reference | ||||
| LDL | Crud | Met/Met | − 6.57 | − 19.06 to 5.91 | 0.30 |
| Val/Met | 6.78 | − 0.77 to 14.33 | 0.07 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | − 3.46 | − 22.29 to 15.37 | 0.71 | |
| Val/Met | 2.44 | − 9.33 to 14.22 | 0.68 | ||
| Val/Val | Reference | ||||
| TC | Crud | Met/Met | − 27.31 | − 63.90 to 9.28 | 0.14 |
| Val/Met | 13.20 | − 9.81 to36.22 | 0.26 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | − 22.16 | − 58.97 to 14.63 | 0.23 | |
| Val/Met | 15.15 | − 7.92 to 38.22 | 0.19 | ||
| Val/Val | Reference | ||||
| AIP | Crud | Met/Met | − 0.03 | − 0.16 to 0.09 | 0.63 |
| Val/Met | 0.09 | 0.01 to 0.18 | 0.01 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | − 0.04 | − 0.17 to 0.08 | 0.50 | |
| Val/Met | 0.09 | 0.01 to 0.17 | 0.02 | ||
| Val/Val | Reference | ||||
| AC | Crud | Met/Met | − 0.23 | − 1.04 to 0.56 | 0.56 |
| Val/Met | 0.47 | − 0.02 to 0.98 | 0.06 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | − 0.26 | − 1.07 to 0.53 | 0.51 | |
| Val/Met | 0.43 | − 0.07 to 0.93 | 0.09 | ||
| Val/Val | Reference | ||||
| LDL/HDL.CRI.II | Crud | Met/Met | 0.01 | − 0.34 to 0.37 | 0.94 |
| Val/Met | 0.13 | − 0.08 to 0.36 | 0.23 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | 0.02 | − 0.32 to 0.37 | 0.88 | |
| Val/Met | 0.10 | − 0.11 to 0.32 | 0.36 | ||
| Val/Val | |||||
| TC/HDL.CRI.I | Crud | Met/Met | 0.05 | − 0.77 to 0.88 | 0.90 |
| Val/Met | − 0.17 | − 0.69 to 0.33 | 0.49 | ||
| Val/Val | Reference | ||||
| Adjusted | Met/Met | 0.01 | − 0.82 to 0.85 | 0.96 | |
| Val/Met | − 0.16 | − 0.68 to 0.35 | 0.53 | ||
| Val/Val | Reference | ||||
Val/Val genotype is considered as a reference. Low adherence of DTAC is considered as a reference. Generalized linear model; crude model and adjusted model Age, physical activity, sex, smoking, alcohol, energy intake, lipid, and glucose-lowering medicines, and family history of diabetes, as covariates. Bold values denote statistical signifcance at the P < 0.05 level.
ORAC oxygen radical absorbance capacity, CI confidence interval, AIP (Atherogenic index of plasma): log(TG/HDL), AC (Atherogenic coefficient): (TC-HDL/HDL), CRI-II (Castelli s risk index): LDL/HDL, CRI-I (Castelli s risk index): TC/HDL, TC total cholesterol, TG triglyceride, HDL high density lipoprotein, LDL low density lipoprotein, WC waist circumference.