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. 2021 Sep 27;11:19130. doi: 10.1038/s41598-021-98544-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Prognostic significance of combinational expression of CALR, HSPA5, and TRIB3 in TCGA-HNSCC patients. The survival curve was recalculated based on the expression of CALR, HSPA5, and TRIB3. (A) Survival curves for high CALR- high HSPA5 group, high CALR-low HSPA5 group, low CALR-high HSPA5 group, and low CALR-low HSPA5 group. (B) Survival curves for high CALR-high TRIB3 group, high CALR-low TRIB3 group, low CALR-high TRIB3 group, and low CALR-low TRIB3 group. (C) Survival curves for high HSPA5-high TRIB3 group, high HSPA5-low TRIB3 group, low HSPA5-high TRIB3 group, and low HSPA5-low TRIB3 group.