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. 2021 Sep 27;11:19130. doi: 10.1038/s41598-021-98544-1

Table 2.

Genes that were selected by 6 keywords and showed high up-regulation or down-regulation under serum starvation.

Key word ID Description NCBI gene ID Fold change after 24 h Fold change after 2 h
Cell growth HSPA1A Heat shock protein family A (Hsp70) member 1A 3303 2.1397336 1.248177638
OSGIN1 Oxidative stress-induced growth inhibitor 1 29,948 2.1668558 1.538782151
UCN Urocortin 7349 2.4790032 1.144155207
BST2 Bone marrow stromal cell antigen 2 684 2.9329562 1.308922836
SGK3 Serum/glucocorticoid regulated kinase family member 3 23,678 3.820176 1.176317287
EDN1 Endothelin 1 1906 0.27418113 0.884857381
PSRC1 Proline and serine rich coiled-coil 1 84,722 0.26818275 0.945457524
S100A9 S100 calcium binding protein A9 6280 0.26209667 1.042621814
S100A8 S100 calcium binding protein A8 6279 0.24599823 1.095810293
CDKN2C Cyclin-dependent kinase inhibitor 2C 1031 0.12124052 0.835693575
Cell death LOC728739 Programmed cell death 2 pseudogene 728,739 2.3000002 1
UCN Urocortin 7349 2.4790032 1.144155207
NPAS2 Neuronal PAS domain protein 2 4862 2.689144 0.930857474
AGR2 Anterior gradient 2, protein disulphide isomerase family member 10,551 2.6983347 1.036070166
PYCR1 Pyrroline-5-carboxylate reductase 1 5831 2.81048 1.165619558
GPR37L1 G protein-coupled receptor 37 like 1 9283 0.3573708 0.929164088
AKR1C3 Aldo–keto reductase family 1 member C3 8644 0.25129116 0.95490666
CTSV Cathepsin V 1515 0.24350072 0.872422377
BNIP3 BCL2-interacting protein 3 664 0.12660438 0.819784126
AXIN2 Axin 2 8313 0.07149426 0.979471303
Cell migration BST2 Bone marrow stromal cell antigen 2 684 2.9329562 1.308922836
ADGRA2 Adhesion G Protein-coupled receptor A2 25,960 3.3248994 1.09175771
CALR Calreticulin 811 3.6909635 0.82266943
SGK3 serum/glucocorticoid regulated kinase family member 3 23,678 3.820176 1.176317287
HSPA5 Heat shock protein family A (Hsp70) member 5 3309 7.4991713 0.83579081
STC1 Stanniocalcin 1 6781 0.20706424 0.782881491
ANLN Anillin actin binding protein 54,443 0.18460144 0.933625648
TCAF2 TRPM8 channel-associated factor 2 285,966 0.13127537 0.750317546
ATOH8 atonal bHLH transcription factor 8 84,913 0.11830313 0.709818819
SERPINB3 Serpin family B member 3 6317 0.11149136 1.039357318
Cell proliferation SGK3 Serum/glucocorticoid regulated kinase family member 3 23,678 3.820176 1.176317287
IKZF3 IKAROS family zinc finger 3 22,806 4.3976007 0.968962725
SPTA1 Spectrin alpha, erythrocytic 1 6708 4.4961443 1.10674307
MIR17HG miR-17-92a-1 cluster host gene 407,975 4.602493 1.283155842
CD22 CD22 molecule 933 5.679524 1.044954641
ID2 Inhibitor of DNA binding 2 3398 0.17407766 1.119070975
ATOH8 Atonal bHLH transcription factor 8 84,913 0.11830313 0.709818819
SERPINB3 Serpin family B member 3 6317 0.11149136 1.039357318
EGLN3 Egl-9 family hypoxia inducible factor 3 112,399 0.100901835 0.74969137
AXIN2 Axin 2 8313 0.07149426 0.979471303
Cell cycle ERN1 Endoplasmic reticulum to nucleus signaling 1 2081 2.9943194 1.146213323
DDIT3 DNA damage-inducible transcript 3 1649 3.1741931 0.597946814
BEX2 Brain expressed X-linked 2 84,707 3.5948327 1.06210961
CALR Calreticulin 811 3.6909635 0.82266943
PIWIL4 Piwi like RNA-mediated gene silencing 4 143,689 3.979958 1.182165243
CENPE Centromere protein E 1062 0.2240672 0.891558939
KCTD11 Potassium channel tetramerization domain containing 11 147,040 0.20453872 0.83617986
MAP2K6 Mitogen-activated protein kinase kinase 6 5608 0.19298029 0.761199796
ID2 Inhibitor of DNA binding 2 3398 0.17407766 1.119070975
CDKN2C Cyclin-dependent kinase inhibitor 2C 1031 0.12124052 0.835693575
Cell adhesion AMIGO1 Adhesion molecule with Ig like domain 1 57,463 2.892857 1.089285831
TNXB Tenascin XB 7148 3.0829856 1.187939406
TNC Tenascin C 3371 3.1931474 1.035432055
FOXA2 Forkhead box A2 3170 3.3726099 0.838221697
CD22 CD22 molecule 933 5.679524 1.044954641
CXCL8 C-X-C motif chemokine ligand 8 3576 0.3170054 0.587415932
SERPINI1 Serpin family I member 1 5274 0.31145853 0.953841739
CDH2 Cadherin 2 1000 0.29494244 1.09390035
CNTN1 Contactin 1 1272 0.26283494 0.835311109
CCL2 C–C motif chemokine ligand 2 6347 0.22852589 0.886680707