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. 2021 Sep 27;12:5654. doi: 10.1038/s41467-021-25903-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Gross necropsy and hematoxylin and eosin (H&E) staining of lung sections from male BALB/c mice (9-month-old) infected with 1200 PFU of MASCp36. Yellow arrow indicates desquamative epithelial cells in bronchiole tubes, cyan arrow indicates edema around vessels, and blue arrow indicates hemorrhage. Representative images are shown (n = 3 per group). b Microscopic observation of lungs showing foamy cells, desquamative epithelial cells, polykaryocytes, fibrin plugs, hyaline membrane, and viral inclusion body (n = 3 per group). c Masson’s trichrome staining of lung sections from male BALB/c mice (9-month-old) infected with 120 PFU of MASCp36 (n = 5 per group) at 7 dpi. Framed areas are shown adjacently at higher magnification.