Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 27;11:19102. doi: 10.1038/s41598-021-98534-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Distinct transcriptomics and pathway profiles of pilocarpine induced TLE in mice. (A) Principal components analysis segregating the transcriptomics profile of the control and pilocarpine induced TLE mice. (B) Frequency of differentially expressed genes binned based on log-fold changes across down- (blue) and up- (yellow) regulated genes. See Table S1 for genes under each bin. (C) Pathway profiles of up- and downregulated genes by log-fold change bin (from B) using Gene Ontology. The − log₁₀(q value) of each pathway was used to plot the heatmap. The lighter-to-darker shades of blue and yellow indicate increasing significance of down- and upregulated pathways, respectively. See Table S2 for the pathways grouped under each theme.