Table 3.
Geometric mean ratio and 90% confidence interval of pharmacokinetic parameters of zolpidem between sexes.
| Male (n = 15) | Female (n = 15) | Geometric mean ratio* (90% CI) |
|
|---|---|---|---|
| Cmax (ng mL−1) | 148.2 | 162.8 | 1.0986 (0.8950–1.3486) |
| AUC0-12 h (h ng mL−1) | 472.8 | 619.5 | 1.3101 (1.0258–1.6733) |
| AUCinf (h ng mL−1) | 501.6 | 664.4 | 1.3246 (1.0151–1.7283) |
*Geometric mean ratio of females to males.
Cmax maximum plasma concentration, AUC0-12 h area under the concentration curve from 0 to 12 h, AUCinf area under the concentration curve from 0 to infinity.