Table 1.
Characteristics of colorectal cancer patients after diagnosis and tumour characteristics at diagnosis according to post-diagnosis intake of sugar-sweetened beverages in the Nurses’ Health Study and the Health Professionals Follow-up Study (n = 1463)a.
| Sugar-sweetened beverage intake, servings | |||
|---|---|---|---|
| <1/week | 1–4/week | ≥5/week | |
| (n = 864) | (n = 415) | (n = 184) | |
| Female, % | 72 | 60 | 71 |
| Age at diagnosis, yrs | 69.1 (8.6) | 67.9 (8.9) | 67.4 (9.0) |
| Food and nutrient intakeb | |||
| SSB intake, servings/d | 0.0 (0.0) | 0.3 (0.2) | 1.3 (0.7) |
| ASB intake, servings/d | 0.5 (0.8) | 0.3 (0.5) | 0.2 (0.5) |
| Fruit juice intake, servings/d | 0.8 (0.7) | 1.0 (0.9) | 1.1 (0.9) |
| Total fructose intake, g/d | 39.6 (12.8) | 47.0 (12.5) | 60.5 (15.2) |
| Total glucose intake, g/d | 38.8 (12.2) | 46.0 (12.1) | 58.9 (14.7) |
| Sucrose intake, g/d | 36.9 (13.9) | 45.2 (13.5) | 59.9 (20.5) |
| Added sugar intake, g/d | 35.8 (16.5) | 50.7 (17.8) | 78.1 (26.2) |
| Alcohol, g/d | 7.7 (12.5) | 6.7 (10.7) | 4.9 (9.7) |
| Folate, mcg/d | 708.3 (355.2) | 667.8 (309.9) | 613.9 (307.1) |
| Calcium, mg/d | 1255.5 (587.4) | 1134.1 (509.5) | 1049.7 (501.2) |
| Vitamin D, IU/d | 562.2 (408.9) | 518.3 (365.4) | 493.3 (435.3) |
| Total energy intake, kcal/d | 1685.9 (542.3) | 1858.1 (547.5) | 2024.5 (586.8) |
| AHEI-2010 | 57.0 (11.4) | 53.6 (10.2) | 47.0 (9.1) |
| Body mass index, kg/m2 | 26.5 (4.9) | 25.8 (4.5) | 26.4 (5.3) |
| Physical activity, MET-h/wk | 18.8 (24.1) | 18.2 (21.8) | 15.4 (19.9) |
| Pack-years of smoking | 16.0 (22.1) | 15.3 (20.4) | 18.3 (25.6) |
| Current smokers, % | 5 | 7 | 6 |
| Regular aspirin use, %c | 34 | 38 | 32 |
| Stage, % | |||
| I | 33 | 33 | 28 |
| II | 32 | 26 | 34 |
| III | 23 | 28 | 24 |
| Unspecified | 12 | 13 | 14 |
| Grade of differentiation, % | |||
| Well | 13 | 16 | 18 |
| Moderate | 59 | 58 | 53 |
| Poor/Undifferentiated | 14 | 12 | 15 |
| Unspecified | 14 | 14 | 14 |
| Cancer subsite, % | |||
| Proximal colon | 44 | 41 | 43 |
| Distal colon | 31 | 32 | 30 |
| Rectum | 21 | 22 | 22 |
| Unspecified | 5 | 5 | 5 |
SSB sugar-sweetened beverages, ASB artificially sweetened beverages, MET metabolic equivalent, AHEI. Alternative Healthy Eating Index.
aMeans (SD) are presented for continuous variables. All variables other than age at diagnosis are age standardised.
bNutrients are energy-adjusted.
cRegular use defined as ≥2 standard (325-mg) tablets of aspirin per week.