Anxiolytic effects of B-GOS® depend on age at supplementation
(A) Rats were gavaged with B-GOS® or vehicle for three weeks during adulthood. Diet groups did not differ in time spent in open arms (p = 0.304).
(B) In the post-wean study, another cohort of rats received supplements in the drinking water after weaning for 5.5 weeks. Diet groups did not differ in time spent in the open arms (p = 0.645).
(C) Gavage animals were pooled (including postnatal and adult gavage) and compared to rats that received supplements in the drinking water after weaning. The delivery mode (gavage vs. water) significantly affected time spent in open arms (p < 0.0001). Data are represented as mean +/− SEM. n.s. = not significant. C = control, B = B-GOS®.