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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: FEBS J. 2021 Apr 12;289(9):2386–2408. doi: 10.1111/febs.15848

Fig. 3. Different pathways associated with fetal testis vascularization.

Fig. 3.

This diagram represents the six key players involved in vascularization during development of the fetal testis. Dashed line indicates areas needing further study. Arrows indicate a positive influence and T-shaped lines indicate an inhibitory effect. WNT, wingless-type MMTV integration site family, member 4; FST, follistatin; SRY, sex determining region on Y chromosome; FGF9; fibroblast growth factor 9; SOX9, SRY (sex determining region Y)-box 9; AMH, anti-Mullerian hormone; VEGFA, vascular endothelial growth factor a; FLT1, VEGFR1; KDR, VEGFR2; PDGFB, platelet-derived growth factor b; PDGFRA/B, platelet-derived growth factor receptor a/b; PROKR2, Prokineticin receptor 2; CDH5, cadherin 5/VE-cadherin.