Table 1.

Summary of toxic effects of cadmium in zebrafish

Toxicity		Ref.
Embryos
Liver	Hepatic lipid accumulation	[20]
Nerve	Neuroglia alterations	[12]
	Increased ATPase activity in brain	[15]
	Reduction of neuronal differentiation and axonogenesis	[14]
	Interference of neural development	[13]
	Anti-estrogen in brain	[16]
	Abnormal somite patterning	[19]
Myoskeletal retina	Eye hypoplasia and hypopigmentation	[18]
Cardiovascular organ	Heart edema and increased pericardial area	[17]
	Activation of cell death pathway in olfactory epithelium	[40]
Olfactory organ	Delay in hatching time	[17]
Others	Tail and axis malformation	[17]
Larvae
Nerve	Circadian rhythms disruption	[22]
Others	Cell death and structural alterations in olfactory epithelium	[21]
Adults
Liver	Carcinogenesis	[45]
	Hepatic lipid accumulation	[23]
	Oxidative damage	[24, 25]
Nerve	Oxidative damage	[25, 26]
Myoskeletal	Structural disorganization, disassembly of muscular myofibrils	[28]
Reproductive organ	Pair spawning reduction and teratogenicity	[27]
	Ovary: oxidative damage	[25]
Retina	Nerve fiber thickening and vacuolating	[29]