Table 4.

Sensitivity, specificity, AUC, and cut-off values for tumor markers as diagnostic indicators.

Factor	Sensitivity (%)	Specificity (%)	AUC	Cut-off value	P
CYFRA21-1	77.6	87	0.875	7.54 ng/ml	<0.001
AFP	98.3	55.3	0.816	0.54 ng/ml	<0.001
CA-153	60.3	86.1	0.773	22.33 U/ml	<0.001
CEA	56.9	89.3	0.738	33 ng/ml	<0.001
CA-199	46.6	87.3	0.661	26 U/ml	<0.001

Sensitivity and specificity were obtained at the cut-off value. P < 0.05 was considered statistically significant.

AUC, area under the curve; CYFRA, cytokeratin fraction; AFP, alpha fetoprotein; CA, cancer antigen; CEA, carcinoembryonic antigen.