TABLE 3.
Multilevel mixed-effects linear regression using natural log transformation based on all MPA measurements except those in the steroid-free arm performed on concomitant steroid therapy (n = 462).
| CS effect on MPA AUC - no concomitant steroid in the steroid-free arm | |||
|---|---|---|---|
| lnAUC | β ln (mg*h/L) | [95% conf. Interval] | p-value |
| Steroid-free arm | −0.077 | −0.15 to −0.0045 | 0.04 |
| MMF (mg) | 0.00028 | 0.00021 to 0.00035 | <0.001 |
| TAC trough level (ng/ml) | −0.0043 | −0.012 to 0.0036 | 0.28 |
| Weight (kg) | −0.0049 | −0.0071 to −0.0027 | <0.001 |
| Time after transplantation (months) | 0.0072 | 0.0017 to 0.013 | 0.01 |
lnAUC = natural log transformation of AUC.