TABLE 1.
Characteristics of the patients included in the Amsterdam and Lombardy cohorts examined with lung ultrasound and computed tomography.
| Characteristic | Amsterdam cohort |
Lombardy cohort |
||
| Focal ARDS N = 14 |
Non-focal ARDS N = 18 |
Focal ARDS N = 9 |
Non-focal ARDS N = 10 |
|
| Age, median (IQR), years | 57 (37–67) | 59 (56–68) | 59 (47–75) | 55 (45–73) |
| Female, no. (%) | 3 (21) | 5 (28) | 4 (44) | 3 (30) |
| Duration of invasive ventilation before enrollment, median (IQR), days | 4 (2–8) | 4 (1–6) | 2 (2–4) | 5 (2–10) |
| ICU mortality, no. (%) | 6 (43) | 6 (33) | 6 (67) | 5 (71)a |
| Global LUS score | 7 (2–9) | 16 (12–18) | 24 (22–25) | 28 (25–31) |
| ARDS severity | ||||
| Mild, no. (%) | 8 (57) | 8 (44) | 3 (33) | 2 (20) |
| Moderate, no. (%) | 5 (36) | 10 (56) | 5 (56) | 6 (60) |
| Severe, no. (%) | 1 (7) | 0 | 1 (11) | 2 (20) |
| Respiratory measures, median (IQR) | ||||
| PaO2 to FiO2 ratio | 255 (135–289) | 199 (138–233) | 176 (113–225) | 152 (103–180) |
| FiO2, % | 50 (40–60) | 60 (50–65) | 50 (40–59) | 50 (50–65) |
| Tidal volume, mL | 503 (411–551) | 433 (349–582) | 450 (340–520) | 450 (325–550) |
| Positive end-expiratory pressure, cm H2O | 7 (5–8) | 10 (8–12) | 5 (5–5) | 5 (5–5) |
| Respiratory rate, breaths/min | 22 (16–25) | 26 (17–35) | 18 (16–25) | 15 (10–16) |
ARDS, acute respiratory distress syndrome; IQR, inter-quartile range; LUS, lung ultrasound; ICU, intensive care unit; PaO2, partial pressure of oxygen; FiO2, fraction of inspired oxygen.
aData available in 7 out of 10 patients.