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. 2021 Sep 14;12:706737. doi: 10.3389/fimmu.2021.706737

Figure 3.

Figure 3

NKp30 expression on circulating NK cells. (A) Flow-cytometry gating strategy for the identification of NK cells and NK cell subsets (CD56dim and CD56bright) in the peripheral blood for receptor repertoire expression analysis. (B–E) Comparison of NK cell receptor expression between healthy donors (HDs) (n = 20) and SS (n = 23) PBMCs, expressed as frequency (B, C) and mean fluorescence intensity (D, E), on total NK cells and NK cell subsets, respectively. (F, G) NKp30 expression on total NK cells [as frequency (F) and MFI (G)] in the pSS cohort segregated by SG histopathology: SG inflammatory infiltration with no feature of lymphomatous lesions (SS), myoepithelial sialadenitis (SS-MESA), and parotid non-Hodgkin’s MALT lymphoma (SS-NHL). The dotted line shows the average of the HD group. Each dot represents one sample/patient. Median with interquartile range in red. Mann–Whitney U t-test. **p < 0.01, ***p < 0.001.