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Integrin αvβ3 inhibitor tetrac abolishes T4-induced suppression of contractile responses of endothelium-denuded sural arteries to methoxamine. Concentration-response relationships to methoxamine obtained after preincubation with T4 or vehicle in the absence (A) or presence (B) of tetrac (3 μM). Number in parentheses represents the number of animals. *p < 0.05 compared to vehicle group (Repeated Measures ANOVA with Tukey’s post hoc test).
